Psychophysical Investigations into the Role of Low-Threshold C Fibres in Non-Painful Affective Processing and Pain Modulation.
We recently showed that C low-threshold mechanoreceptors (CLTMRs) contribute to touch-evoked pain (allodynia) during experimental muscle pain.Conversely, in absence of ongoing pain, Incline Switch Assembly the activation of CLTMRs has been shown to correlate with a diffuse sensation of pleasant touch.In this study, we evaluated (1) the primary affe